Dr. Stephen Phinney on Nutritional Ketosis and Ketogenic Diets (Part 1)

Learn more at https://www.virtahealth.com/thevirtatreatment

Read more by Dr. Stephen Phinney at: https://blog.virtahealth.com/author/stephenphinney/

Stephen Phinney, MD, Ph.D, explains the science of nutritional ketosis, a natural metabolic state in which your body is fueled mainly by fats and ketones, instead of carbohydrates (glucose). Nutritional ketosis occurs when you follow a ketogenic diet.

Watch part 2 here: https://youtu.be/CHJmqhMzKtE
Watch part 3 here: https://youtu.be/k0NE8WEH44A

Stephen Phinney is the Chief Medical Officer and Co-Founder of Virta Health, the first clinically-proven treatment to safely and sustainably reverse type 2 diabetes without medications or surgery.

As a physician-scientist with 40 years of experience divided between academic internal medicine and industry, Dr. Phinney has studied nutritional biochemistry with a long-term focus on low carbohydrate research and its benefits for physical performance and insulin sensitivity.

A Professor of Medicine Emeritus at University of California, Davis, Dr. Phinney is an internationally recognized expert on obesity, carbohydrate-restricted and ketogenic diets, diet and performance, and essential fatty acid metabolism.

Dr. Phinney has designed, completed, and published data from more than 20 clinical protocols involving diets, exercise, oxidative stress, and inflammation. His extensive experience in the design of clinical nutrition trials in both academic and industrial settings has led to more than 87 peer-reviewed papers and book chapters on clinical nutrition and biochemistry. He is the author of four books, including The Art and Science of Low Carbohydrate Living and The Art and Science of Low Carbohydrate Performance, two foundational books on low carb nutrition science and nutritional ketosis that he co-authored with Jeff Volek, Ph.D, RD.

Dr. Phinney received his medical degree from Stanford University, holds a Doctorate in nutritional biochemistry and metabolism from the Massachusetts Institute of Technology and completed post-doctoral research at Harvard University.


  1. Dan Carbone on February 12, 2020 at 7:35 pm

    Who is here because of Martin cabello

  2. GIANLUCA TOPPI on February 12, 2020 at 7:35 pm

    I just started the Keto diet… I bought the Keto meter here. I m 0.2. So happy.. thanks for the amazing video . https://www.ebay.co.uk/itm/372731815230

  3. SXT Wellness Coaching on February 12, 2020 at 7:38 pm

    Ketosis is good if you need it

  4. Skylar Morris on February 12, 2020 at 7:39 pm

    This man is amazing!!!!

  5. Anita Burke on February 12, 2020 at 7:39 pm

    I had a brain tumor removed 2 years ago and turned down radiation therapy

    Staying in nutritional ketosis is pretty important to me. From what I understand, ketone bodies cannot be used as fuel by cancer cells

  6. Zaori on February 12, 2020 at 7:40 pm

    SUGAR is causing chronic diseases! Cancer LIVES of sugar! Think about it! Do Keto!

  7. Rene Hernandez on February 12, 2020 at 7:40 pm

    I don’t think Jillian Michaels would agree. Lol.

  8. bashhhe on February 12, 2020 at 7:41 pm

    Keto changed my perception of nutrition. I am 100% keto no cheating. Vast majority of my health issues especially hormonal related got fixed and never returned such as high androgens, PCOS, acne, pms, heavy period bleedin, cramping, indigestion, depression, weak imune system, respiratory infections. This are all gone ever since. I am living a healthy and mentaly happy life, full of hope. We are what we eat. 🥬🥒🥦🍓🍋🥕🥑🍆

  9. domnic0 on February 12, 2020 at 7:44 pm

    Fasting is good to do once or twice a year. It’s bullshit that fasting is not good to do!

  10. Brother Bryan on February 12, 2020 at 7:47 pm

    Thank you very much, excellent resource material, and excellently done.

  11. Anstria Tarot on February 12, 2020 at 7:48 pm

    Excellent video and veery much appreciated.

  12. Bobby Ocampo on February 12, 2020 at 7:48 pm

    My HBA1C decreased from 10.2 to 7.5 in one month.

  13. Joe Sysk on February 12, 2020 at 7:50 pm

    Got to disagree about coffee,I was hooked for 30 years,started 1pot a day,ended on 3 pots a day,I was so dehydrated, didn’t realize,how bad I was hooked,Drink water.My doctor said 3 pots was ok, LMFAO, watched a show I think Wendy Williams,she was diagnosed with stomach cancer from constantly drinking coffee,that’s what got me to kick it.

  14. Think 4 Yourself on February 12, 2020 at 7:50 pm

    Keto is only good short term. Break insulin resistance, or other disease, then break ketosis. It will wreck testosterone and rob nutrients otherwise.

  15. Majid ben on February 12, 2020 at 7:51 pm

    I have lost 22 lb and feel great and eat less in just a month. All I did is reducing my carbs from 200+ gr a day to less than 80 gr. And I started to fast using 8/16 formula than I fasted 24h and 40h.
    I was able to fast with absolutely no problem because I don’t crave sugar anymore. I can say with confidence that I am out of sugar addiction. My blood pressure went down to normal after being prescribed medication that I never accepted to take.
    I used to run a lot, half marathons and full marathons but was running on carbohydrates. As soon as I slowed my exercising due to injuries I gained a lot of weight and went back to square one.
    I think my body is now adapted to ketones as I just did 48 h fasting and feel great.
    I will never go back to carbs again. I am refining my diet by listening to my body. This is life-changing information.
    Thank you, Dr. Stephen, for being part of this scientific movement. Our health system is not working. If I followed what was prescribed to me, I would have a miserable life without a doubt.

  16. Simon trow on February 12, 2020 at 7:52 pm

    im on keto….i.eat meat veg salad…an 6 eggs aday…..2 meal aday in a 6 hour window……is 6 eggs aday to much??

  17. Total Body Fitness on February 12, 2020 at 7:53 pm

    The key here is following the diet properly. As an exercise physiologist and health coach for the last 3 decades, I have had countless people come to me in horrible health after following a ketogenic diet. What I find is that a lot of people think they can eat any kind of meats including fried pork and they will be fine. I have people that eat bacon/pork sausage and eggs on a daily basis and their health has deteriorated. I have others with low testosterone and other hormonal deficiencies due to eating animals that were injected with hormones. Following the diet properly is key and a lot of people lack direction and end up in worse health!

  18. the best of keto on February 12, 2020 at 7:54 pm

    With a simple keto diet and discipline, I have lost 32 pounds since November 12, 2019. I started with 235 pounds and I’m 203 now! Keto is not just a diet, for me is a lifestyle that save lives! I’m looking forward to lose the next 20 pounds!

  19. Nor Yahya on February 12, 2020 at 7:56 pm

    ياعمي عايزين الترجمة

  20. You Tuber on February 12, 2020 at 7:59 pm

    It is called a ‘ketogenic diet’. Sounds scientific.
    But what it is is simply eating the foods, and only the foods, our bodies are evolved to process.
    The things available to us in nature, the things we naturally crave – natural fats, salt, meats, greens, autumnal fruits.

  21. God‘s Channel on February 12, 2020 at 7:59 pm

    The Keto Diet also helps with Gallstones.

  22. Tamia Mcfarland on February 12, 2020 at 7:59 pm

    I have tried everything. I gained weight in places where I didn’t want them. It was a struggle to get them off. Weight in my stomach, thighs, and definitely my CHEEKS!! I’m so thankful I found https://mmini.me/YourKetoDiet I wanted a change that worked fast and stay consistent! I cut out junk food and processed foods, and drink plenty of water with minimal exercises and stayed consistent with my KETO diet. I hope it helps and inspires others! Now I kickbox and personal train people that need help too!

  23. Klemmy123 on February 12, 2020 at 8:00 pm

    I’m a Leiden Factor 5 Heterozygote with Thrombophilia (I take 4mg of Warfarin a Day) , can I still start a Keto diet???

  24. Health Cider on February 12, 2020 at 8:01 pm

    Guys if you want to lose 2pounds weight then go and do it with this hack https://many.link/health_cider

  25. Green Tea on February 12, 2020 at 8:03 pm

    Hmmmm. Blue Zones my friend, blue Zones. They eat high carb diets and are the healthiest people on the planet. But, no mention of that?

  26. TheCompleteGuitarist on February 12, 2020 at 8:03 pm

    Is a carnivore diet Ketogenic?

  27. A. Z. on February 12, 2020 at 8:04 pm

    Did he just say ‘I was feelung my oats" ??? Around 00:57 ??? Gia Gunn is quaking!

  28. GIANLUCA TOPPI on February 12, 2020 at 8:04 pm

    Hi. I just bought this ketosi meter here!!! Good staff . Can not wait ..https://rover.ebay.com/rover/0/0/0?mpre=https%3A%2F%2Fwww.ebay.co.uk%2Fulk%2Fitm%2F372731815230

  29. Ai Angel on February 12, 2020 at 8:05 pm

    Martin Cabello III brought me here.

  30. Tom Mackenzie on February 12, 2020 at 8:06 pm

    Scientist-physician is a rare breed. Great education video.

  31. Denise Girmer on February 12, 2020 at 8:07 pm

    What a BLESSING you are dear Dr! God bless and protect you in the New yr❤️😍

  32. bible bill on February 12, 2020 at 8:09 pm

    Elizabeth Casparro, MPH,RD Nutrition & Dietetics                                                                                  The two main functions of carbohydrates in the body are to provide energy for all cells and spare the use of protein from the muscles and organs. When deprived of carbohydrates, our bodies can survive off of protein and fat, but only for a limited time. When we turn fat and protein into energy (a process called ketosis), we produce ketones (acidic compounds) that raises our blood acidity. If continued, being in this state called ketosis/ketoacidosis, can eventually lead to death.

  33. Elmo on February 12, 2020 at 8:11 pm

    Fantastic video, bravo. 👏

  34. keto1year Robert on February 12, 2020 at 8:12 pm

    bullshit to vegetables………………….. i will not eat the vegetables, and their chemicals…

  35. The New Neander's Medical on February 12, 2020 at 8:14 pm

  36. Mary on February 12, 2020 at 8:15 pm

    Have your own customized keto diet here: https://tinyurl.com/tykvce3

  37. squiffedallday on February 12, 2020 at 8:17 pm

    I’m On day 5 of keto and OMAD. My ketones were reading very high and the doctor wanted me to come in for a urine test. The test showed I was at 80.

    Should I be concerned for ketoacidosis?

    One doc told me to stop keto now and another said this is normal from how hard I hit keto and OMAD. Anyone have experience with heavy ketones?

  38. Jeepgurl on February 12, 2020 at 8:19 pm

    Finally! Thank you so much for this video series Dr. Phinney! I appreciate your (and Dr. Volek’s) theoretical mind and quest for truth. You sirs are true scientists! I have a pot if bone broth on the stove right now as I’m watching your presentation.

  39. Infinity Creations on February 12, 2020 at 8:19 pm

    high protein ingestion (in the absence of Carbohydrates) will not affect ketosis as increases in insulin production will necessarily result in increase of glucagon thus the insulin/glucagon ratio will remain the same. The impact on insulin resistance is debatable in my opinion but high protein in the absence of carbs will not necessarily impact the state of nutritional ketosis. See B.Bikman

  40. Belly Button on February 12, 2020 at 8:20 pm

    pepega TL;DR: Butter your toast, but the toast is not there.

  41. Intissar Abid on February 12, 2020 at 8:21 pm

    This is typically the best video I have ever watched on Keto Diet .. It feels good to listen to people who perfectly know what they are talking about .. Hands down

  42. David Ronson on February 12, 2020 at 8:21 pm

    The first time I see a doctor warning people who have medical conditions instead than one size fits all

  43. Happy Christian on February 12, 2020 at 8:21 pm

    Does eating lots of spinach make your blood thick?

  44. Super Fata on February 12, 2020 at 8:23 pm

    I was 106 KG (116 at my heaviest) last summer, felt terrible. I had digestive problems, stomach aches, joint and body aches, low energy, acne, bad skin (both fat and dry in different areas) and high blood pressure, just to mention a few health issues.
    I started doing a ketogenic diet, intermittent fasting (8/16) and walking 10 000 steps each day in late August.
    In under 4 months, I lost 18 KG. ALL my health issues were gone. Blood pressure like 25-year-old (I´m 45).
    In late December I went back to a "normal" diet, listening to my doctors "advice". Two months in and I feel really sick. I´m going back to healthy keto and intermittent fasting permanently. Best thing I ever did!

  45. jay hern on February 12, 2020 at 8:23 pm

    this man saved my life.

  46. Mr. Husky on February 12, 2020 at 8:25 pm

    I eat one meal a day, keto, and my energy levels are through the roof. Adapting is not fun however, fatigue is real and heavy, and it’s easy to feel bloated on fats as your body is shifting. It doesn’t feel good whatsoever; large salads and OMAD gave me fiber and time for digestion, which helped immensely. BUT…
    …once you’re adapted…get ready. I also workout on this too, three hard workouts/week, some form of interval or HIIT training with a little bit of weights and always long stretching sessions afterward. Otherwise I walk three miles/day, including on heavy workout days too. Still doing OMAD. Age: 35.

  47. Uxi Jefferies on February 12, 2020 at 8:28 pm

    Dr. Phinney you’re wonderful and I admire you greatly for the way you have approached your education on this subject.

  48. Nicola Worrell on February 12, 2020 at 8:29 pm

    I am not sure if you are able to answer a question Dr. Phinney but I was wondering what your views are on carb cycling. I am currently following a keto lifestyle. Thanks

  49. markus Hantzl on February 12, 2020 at 8:29 pm

    Nice Recipes,
    I made a Keto diet and had top results but having a plan is very important.

  50. SXT Wellness Coaching on February 12, 2020 at 8:33 pm

    Great video to include those high protein and high fat foods. I do similar videos on my channel if you want to click and check it out?